Newswire (Published: Thursday, December 13, 2018, 4:01:00 PM CST, Received: Thursday, December 13, 2018, 4:14:19 PM CST)

Word Count: 320

By a News Reporter-Staff News Editor at Cancer Weekly -- A new study on Oncology - Prostate Cancer is now available. According to news reporting originating from Cork, Ireland, by NewsRx correspondents, research stated, "Aims Accurate preoperative knowledge of tumor stage is important in preoperative planning at radical prostatectomy (RP). The aim of this study was to assess the predictive ability of multiparametric MRI for detecting pathological outcomes."

Our news editors obtained a quote from the research from Cork University Hospital, "A retrospective review was performed of all patients who underwent RP over a 4 year period. Preoperative MRI was reported as showing T3 or T4 disease in 26(17.9%) out of 145 patients undergoing RP. Of these, 10(6.9%) had ECE (extra-capsular extension) and 1(0.7%) had SVI (seminal vesicle invasion) on final histology. The sensitivity and specificity of MRI for detecting ECE were 27.3% and 87.6%, respectively. The sensitivity and specificity of MRI for detecting SVI were 11.1% and 97.8%, respectively. The positive predictive values for determining ECE and SVI were 45.5% and 25%, respectively and negative predictive values were 75.9% and 94.4%."

According to the news editors, the research concluded: "MRI has good specificity but poor and heterogeneous sensitivity for predicting T3 disease in RP specimen."

For more information on this research see: The Predictive Ability of Pre-Operative Magnetic Resonance Imaging to Detect Pathological Outcomes in Prostate Cancer. Irish Medical Journal, 2018;111(7):790 (see also Oncology - Prostate Cancer).

The news editors report that additional information may be obtained by contacting G.J. Nason, Dept. of Urology, Cork University Hospital, Wilton, Cork, Ireland. Additional authors for this research include L. Selvarajah, E.M. O'Connor, J. O'Kelly, S.W. Considine, B. Moss, D. MacMahon, J. Heneghan, N. Meyer, J. Buckley, K. O'Regan and M.F O'Brien.

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