Newswire (Published: Thursday, October 24, 2019, Received: Thursday, October 24, 2019, 4:31:38 PM CDT)

Word Count: 481

2019 OCT 24 (NewsRx) -- By a News Reporter-Staff News Editor at Chemicals & Chemistry Daily Daily -- Data detailed on Oncology - Prostate Cancer have been presented. According to news reporting from Inner Mongolia, People’s Republic of China, by NewsRx journalists, research stated, “This study aimed to explore the efficacy of radical prostatectomy (RP) combined with endocrine drugs on elderly patients with prostate cancer (PCa). A retrospective analysis was performed for the data of 70 patients with PCa, who were divided into the control group (RP) and the observation group (RP combined with endocrine drugs) according to treatment methods.”

The news correspondents obtained a quote from the research from the Department of Urology Surgery, “Patients in the two groups were compared in terms of prostate volume, serum prostate specific antigen (PSA) concentration, operative time, intraoperative bleeding, volume of drainage fluid, time of indwelling catheter, time of lymph node dissection, hospital stay, positive margin rate, rate of positive lymph nodes, bladder neck invasion, seminal vesicle invasion and bone metastasis. The patients were followed up to record the biochemical recurrence-free rate and grouped based on different parameters to analyze the biochemical recurrence-free survival rates. Compared with the control group, patients in the observation group had significantly lower prostate volume and serum PSA level (both P< 0.05), significantly greater operative time and intraoperative bleeding but significantly lower volume of drainage fluid and time of indwelling catheter (all P< 0.05), significantly lower positive margin rate, rate of positive lymph nodes, and bone metastasis (P < 0.05). The 5-year biochemical recurrence-free rate in the observation group was significantly higher than that in the control group (P < 0.05), and the rate in patients with postoperative positive bone and lymph node metastases was significantly higher than that in patients with negative bone and lymph node metastases.”

According to the news reporters, the research concluded: “RP combined with endocrine drugs in the treatment of elderly patients with PCa reduces prostate volume, PSA level, positive margin rate of tumors and rate of positive lymph nodes, and significantly reduces the 5-year biochemical recurrence rate, with a good long-term effect.”

For more information on this research see: Efficacy of Radical Prostatectomy Combined With Endocrine Drugs In Treatment of Elderly Patients With Prostate Cancer. INTERNATIONAL JOURNAL OF CLINICAL AND EXPERIMENTAL MEDICINE, 2019;12(9):11420-11427. INTERNATIONAL JOURNAL OF CLINICAL AND EXPERIMENTAL MEDICINE can be contacted at: E-Century Publishing Corp, 40 White Oaks Ln, Madison, WI 53711, USA.

Our news journalists report that additional information may be obtained by contacting B. Chen, Tongliao City Hosp, Dept. of Urology Surgery, 668 Horqin St, Tongliao 028000, Inner Mongolia, People’s Republic of China. Additional authors for this research include G. Hang, Q. Wen, L.X. Bao, Z.Q. Xu and Y.G. Wan.

(Our reports deliver fact-based news of research and discoveries from around the world.)

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