Newswire (Published: Thursday, December 20, 2018, 12:01:00 PM CST, Received: Thursday, December 20, 2018, 12:06:19 PM CST)

Word Count: 324

By a News Reporter-Staff News Editor at Cancer Weekly -- Data detailed on Oncology - Prostate Cancer have been presented. According to news originating from New York City, New York, by NewsRx correspondents, research stated, "Androgen-deprivation therapy (ADT) entails lowering serum testosterone levels to castrate levels and forms a cornerstone of the management of hormone-sensitive advanced prostate cancer; however, the benefit of ADT is partially offset by its detrimental metabolic and cardiovascular adverse effects."

Our news journalists obtained a quote from the research from Memorial Sloan-Kettering Cancer Center, "ADT decreases insulin sensitivity while promoting dyslipidemia and sarcopenic obesity, which leads to an increased risk of cardiovascular morbidity and potentially mortality. The risk seems to be highest in elderly patients who have had recent cardiovascular events before starting ADT."

According to the news editors, the research concluded: "It is prudent to engage in an individualized risk-benefit discussion and develop a cohesive multidisciplinary management plan to medically optimize and closely observe these patients before and during treatment with ADT."

For more information on this research see: Cardiovascular and Metabolic Effects of Androgen-Deprivation Therapy for Prostate Cancer. Journal of Oncology Practice, 2018;14(10):580-587,119. Journal of Oncology Practice can be contacted at: Amer Soc Clinical Oncology, 2318 Mill Road, Ste 800, Alexandria, VA 22314, USA (see also Oncology - Prostate Cancer).

The news correspondents report that additional information may be obtained from D. Gupta, Mem Sloan Kettering Canc Center, New York, NY 10065, United States. Additional authors for this research include K.L. Chuy, J.C. Yang, M. Bates, M. Lombardo and R.M. Steingart.

The direct object identifier (DOI) for that additional information is: https://doi.org/10.1200/JOP.18.00178. This DOI is a link to an online electronic document that is either free or for purchase, and can be your direct source for a journal article and its citation.

(Our reports deliver fact-based news of research and discoveries from around the world.)

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Science and Technology
      Scientific Research
Health and Wellness
      Medical Conditions and Diseases
            Cancer
                  Prostate Cancer
            Men's Health Issues
                  Prostate Cancer
      Treatments and Therapies
            Cardiometabolic Care