Newswire (Published: Thursday, October 8, 2020, Received: Thursday, October 8, 2020, 6:31:42 PM CDT)

Word Count: 552

2020 OCT 08 (NewsRx) -- By a News Reporter-Staff News Editor at Cancer Daily -- Investigators discuss new findings in Oncology - Prostate Cancer. According to news reporting out of Miami, Florida, by NewsRx editors, research stated, “We report short-term outcomes of focal high intensity focused ultrasound use for primary treatment of localized prostate cancer. Single-center prospectively collected data on patients with prostate cancer who underwent primary focal high intensity focused ultrasound from January 2016 to July 2018 were included.”

Our news journalists obtained a quote from the research from the University of Miami, “All patients underwent a 12-core biopsy with magnetic resonance imaging-ultrasound fusion biopsy depending on the presence of targetable lesions. Any Grade Group was allowed, however only patients with localized disease were included. The primary outcome was oncologic control, defined as negative followup in-field biopsy of treated cancer. Prostate specific antigen, Sexual Health Inventory for Men, International Prostate Symptom Score and Expanded Prostate Cancer Index Composite domain scores were assessed 3-monthly till 12 months. Biopsy was performed at 6 or 12 months for high or low/intermediate risk cancer, respectively. Fifty-two patients with minimum followup of 12 months were included in the study. The majority of patients (67%) had cancer Grade Group 2 or greater. Fifteen patients (28.8%) underwent complete transurethral prostate resection/holmium laser enucleation of prostate procedure for debulking large prostates to avoid postoperative urinary retention. Among 30 (58%) patients who underwent followup biopsies, 25 (83%) had negative in-field biopsy results and 4 (13%) had de-novo positive out-of-field biopsy. Only 5 major complications (all grade III) in 4 patients were noted. Urinary symptoms returned to near baseline questionnaire scores within 3-6 months. Sexual function returned to baseline at 12 months. Focal high intensity focused ultrasound is a safe and effective treatment for patients with localized clinically significant prostate cancer with acceptable short-term oncologic and functional outcomes. The complications are minimal and patient selection is essential.”

According to the news editors, the research concluded: “Short-term oncologic outcomes are promising but longer followup is required to establish long-term oncologic outcomes.”

This research has been peer-reviewed.

For more information on this research see: Prospective Evaluation of Focal High Intensity Focused Ultrasound for Localized Prostate Cancer. Journal of Urology, 2020;204(3):483-489. Journal of Urology can be contacted at: Lippincott Williams & Wilkins, Two Commerce Sq, 2001 Market St, Philadelphia, PA 19103, USA. (Elsevier - www.elsevier.com; Journal of Urology - http://www.journals.elsevier.com/journal-of-urology/)

Our news journalists report that additional information may be obtained by contacting Dipen J. Parekh, University of Miami, Dept. of Urology, Miller School of Medicine, 1120 Nw 14TH St, Suite 1551S, Miami, FL 33136, United States. Additional authors for this research include Bruno Nahar, Abhishek Bhat, Nachiketh Soodana-Prakash, Maria F. Becerra, Diana Lopategui, Vivek Venkatramani, Ronak Patel, Vinayak Madhusoodanan, Oleksandr N. Kryvenko, Chad R. Ritch, Mark L. Gonzalgo, Sanoj Punnen and Isildinha M. Reis.

The direct object identifier (DOI) for that additional information is: https://doi.org/10.1097/ju.0000000000001015. This DOI is a link to an online electronic document that is either free or for purchase, and can be your direct source for a journal article and its citation.

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