Newswire (Published: Wednesday, April 24, 2019, Received: Wednesday, April 24, 2019, 4:39:29 PM CDT)

Word Count: 468

2019 APR 24 (NewsRx) -- By a News Reporter-Staff News Editor at Disease Prevention Daily -- A new study on Oncology - Prostate Cancer is now available. According to news reporting from Utrecht, Netherlands, by NewsRx journalists, research stated, “To examine the clinical features, applied treatments, and survival of older patients with prostate cancer compared with younger patients. All patients diagnosed with prostate cancer between 2005 and 2015 in the Netherlands were identified from the nationwide population-based Netherlands Cancer Registry (NCR).”

The news correspondents obtained a quote from the research from the Department of Research, “Patient and tumour characteristics, as well as applied treatments, were described by age groups and prognostic risk groups. Relative survival rates were determined, including multivariable relative survival regression analyses. Additionally, to assess if age was associated with receiving curative treatment, a multivariable logistic regression analysis was performed. In total, 48% of all patients were 70 years of age or older. Older patients had a higher prostate specific antigen (PSA) level, a higher Gleason score, as well as a higher disease stage at diagnosis. The 10-year relative survival decreased with increasing age, and after adjustment for disease stage, Gleason score, PSA level, and comorbidities, older patients had a worse survival rate. Older patients with intermediate- or high-risk disease appeared to be treated less often with curative intent compared with younger patients after adjustment for tumour stage, Gleason score, PSA level, and comorbidities. Older patients with intermediate/high risk prostate cancer treated with curative intent showed a 10-year relative survival rate similar to younger patients. The survival of older patients was worse than younger patients. This might be due to suboptimal treatment, as older patients were less often treated with curative intent.”

According to the news reporters, the research concluded: “Although the increased risk of treatment complications should be considered, age alone should not be a decisive factor when offering a treatment.”

For more information on this research see: Nationwide Treatment Patterns and Survival of Older Patients With Prostate Cancer. Journal of Geriatric Oncology, 2019;10(2):252-258. Journal of Geriatric Oncology can be contacted at: Elsevier Science Bv, PO Box 211, 1000 Ae Amsterdam, Netherlands. (Elsevier - www.elsevier.com; Journal of Geriatric Oncology - http://www.journals.elsevier.com/journal-of-geriatric-oncology/)

Our news journalists report that additional information may be obtained by contacting K.K.H. Aben, Netherlands Comprehens Canc Org, Dept. of Research, Utrecht, Netherlands. Additional authors for this research include R.W.M. Vernooij, I. van Oort and T.M. de Reijke.

The direct object identifier (DOI) for that additional information is: https://doi.org/10.1016/j.jgo.2018.06.010. This DOI is a link to an online electronic document that is either free or for purchase, and can be your direct source for a journal article and its citation.

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Western Europe
Netherlands
Europe
Amsterdam
Utrecht

Subjects

Science and Technology
      Scientific Research
            Medical Research
Health and Wellness
      Medical Conditions and Diseases
            Cancer
                  Prostate Cancer
            Men's Health Issues
                  Prostate Cancer
      Health Sciences
            Medical Research