Newswire (Published: Thursday, April 11, 2019, Received: Thursday, April 11, 2019, 3:36:24 PM CDT)
Word Count: 720
2019 APR 11 (NewsRx) -- By a
Despite the trend toward declining or stabilizing rates, prostate cancer remains the second most commonly diagnosed cancer and the sixth leading cause of cancer death among men worldwide, said the study’s lead author,
“Previous studies have indicated significant variation in prostate cancer rates, due to factors including detection practices, availability of treatment, and genetic factors,” Freeman said. “By comparing rates from different countries, we can assess differences in detection practices and improvements in treatment.”
Researchers examined prostate cancer incidence and mortality patterns across five continents using the most recent cancer incidence data from the
Of the 44 countries examined for incidence data, prostate cancer rates during the most recent five-year period increased in four countries, with
Among the 71 countries analyzed for mortality rates, rates decreased in 14 countries, increased in three countries, and remained stable in 54 countries.
Globally, as of 2012, prostate cancer was the most commonly diagnosed cancer among men in 96 countries and the leading cause of death in 51 countries.
Other findings: - The highest incidence rates in the most recent five-year period were found in
Freeman said she and colleagues were surprised and pleased to see that so many nations have achieved stability in prostate cancer rates, meaning that rates have not increased during the period examined. In coming years, she said, global health experts would hope for more nations to move from stability toward decreasing incidence and mortality rates.
Freeman said the study confirmed the impact of prostate-specific antigen (PSA) screening. She explained that in
Freeman pointed out that some nations plan to scale back recommendations for PSA screening, as it is believed to lead to diagnosis and possible overtreatment of prostate cancer cases that would never become symptomatic.
“Overall, patients should be having an informed discussion with their providers about the benefits and harms of PSA testing for detection of prostate cancer,” she said. “Future studies should monitor trends in mortality rates and late-stage disease to assess the impact of reduction in PSA testing in several countries.”
Freeman said one limitation of the study is the variability in data among different countries. For example, some countries may have only collected data from certain geographic areas, whereas others may have collected data from the whole nation. However, she added that the breadth of data in this study allowed researchers to draw a comprehensive portrait of prostate cancer incidence and mortality around the world.
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