Newswire (Published: Tuesday, November 12, 2019, Received: Tuesday, November 12, 2019, 3:49:41 PM CST)

Word Count: 533

2019 NOV 12 (NewsRx) -- By a News Reporter-Staff News Editor at Clinical Trials Daily -- Research findings on Oncology - Prostate Cancer are discussed in a new report. According to news reporting out of Piscataway, New Jersey, by NewsRx editors, research stated, “Fatigue is often one of the most commonly reported symptoms in prostate cancer survivors, but it is also one of the least understood cancer-related symptoms. Fatigue is associated with psychological distress, disruptions in sleep quality, and impairments in health-related quality of life.”

Funders for this research include National Cancer Institute, Rutgers Cancer Institute of New Jersey, University of New Mexico, New Jersey Alliance for Clinical Translational Science; NJ ACTS, UNM Comprehensive Cancer Center.

Our news journalists obtained a quote from the research from Rutgers University, “Moreover, inflammatory processes and changes related to the hypothalamic-pituitary-adrenal (HPA) axis and/or autonomic nervous system may also play a role in cancer-related fatigue. Thus, effective treatments for fatigue in prostate cancer survivors represent a current unmet need. Prior research has shown that Tai Chi Qigong, a mind-body exercise intervention, can improve physical and emotional health. Herein, we describe the protocol of the ongoing 3-arm randomized controlled Health Empowerment & Recovery Outcomes (HERO) clincal trial. One hundred sixty-six prostate cancer survivors with fatigue are randomized to a modified Tai Chi Qigong intervention (TCQ), intensity-matched body training intervention (BT), or usual care (UC) condition. Guided by biopsychosocial and psychoneuroimmunology models, we propose that TCQ, as compared to BT or UC will: i) reduce fatigue (primary outcome) in prostate cancer survivors; ii) reduce inflammation; and iii) regulate the expression of genes from two major functional clusters: a) inflammation, vasodilation and metabolite sensing and b) energy and adrenergic activation. Assessments are conducted at baseline, the 6-week midpoint of the intervention, and 1 week, 3 months, and 12 months post-intervention. If our findings show that TCQ promotes recovery from prostate cancer and its treatment, this type of intervention can be integrated into survivorship care plans as the standard of care.”

According to the news editors, the research concluded: “The study’s findings will also provide novel information about underlying biobehavioral mechanisms of cancer-related fatigue.”

For more information on this research see: Biobehavioral effects of Tai Chi Qigong in men with prostate cancer: Study design of a three-arm randomized clinical trial. Contemporary Clinical Trials Communications, 2019;16():100431.

Our news journalists report that additional information may be obtained by contacting A.Y. Kinney, Dept. of Biostatistics and Epidemiology, School of Public Health, Rutgers University, Piscataway, NJ, United States. Additional authors for this research include C.K. Blair, D.D. Guest, J.K. Ani, E.M. Harding, F. Amorim, T. Boyce, J. Rodman, C.G. Ford, M. Schwartz, L. Rosenberg, O. Foran, J. Gardner, Y. Lin, W. Arap and M.R Irwin.

The direct object identifier (DOI) for that additional information is: https://doi.org/10.1016/j.conctc.2019.100431. This DOI is a link to an online electronic document that is either free or for purchase, and can be your direct source for a journal article and its citation.

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