Newswire (Published: Thursday, February 7, 2019, 11:02:00 AM CST, Received: Thursday, February 7, 2019, 11:38:33 AM CST)

Word Count: 618

By a News Reporter-Staff News Editor at Cancer Weekly -- Current study results on Oncology - Prostate Cancer have been published. According to news reporting from Durham, North Carolina, by NewsRx journalists, research stated, "There are multiple treatment options for men with localized prostate cancer that provide similar curative efficacy but differ in their impact on sexual functioning. To evaluate the psychometric properties of the Patient-Reported Outcomes Measurement Information System (PROMIS) SexualFunction and Satisfaction (SexFS) measures, including items from versions 1 and 2 of the short forms."

Funders for this research include Agency for Healthcare Research and Quality, National Cancer Institute (see also Oncology - Prostate Cancer).

The news correspondents obtained a quote from the research from Duke University, "A population-based cohort of men across North Carolina completed surveys via phone interviews at baseline (prior to treatment) and at 3, 12, and 24 months after cancer treatment initiation. Surveys included the PROMIS SexFS domains of interest in sexual activity, erectile function, orgasm, and satisfaction and the Prostate Cancer Symptom Indices. Analyses included descriptive statistics, assessment of structural validity using confirmatory factor analysis and itemresponse theory, tests for differential item functioning, assessment of convergent validity using correlations, and evaluation of responsiveness of the PROMIS SexFS measures over time. We hypothesized that men undergoing surgery (prostatectomy) would report the poorest sexual function at the 3-month survey. Sample size varied by assessment point and ranged from 332. 939men, consisting of 30% non-white men, and 30% of the sample had a high school degree or less. The items within the PROMIS orgasm domain did not form a unidimensional scale. PROMIS measures of interest in sexual activity, erectile function, and satisfaction were unidimensional and highly correlated with related Prostate Cancer Symptom Indices measures (eg, erectile function, r = 0.84-0.95). Erectile function in the surgery group declinedmore at 3 months compared to the no-surgery group (2 points); this difference narrowed at 12 and 24months after surgery, as the surgery group recovered over time. Results were similar for PROMIS Interest in Sexual Activity and PROMIS Satisfaction scales. The PROMIS SexFS measures may be used to identify effective interventions to treat sexual dysfunction and monitor sexual functioning in men with prostate cancer over time. Strength & Limitations: This study was limited to men living in North Carolina who could self-report their health-related quality of life in English. However, this study was able to include more men from vulnerable populations by allowing them to self-report over the phone."

According to the news reporters, the research concluded: "This study provided strong support for use of the PROMIS SexFS (version 2) measures in men with localized prostate cancer to assess sexual interest, erectile function, and satisfaction over time."

For more information on this research see: Psychometric Evaluation of PROMIS Sexual Function and Satisfaction Measures in a Longitudinal Population-Based Cohort of Men With Localized Prostate Cancer. The Journal of Sexual Medicine, 2018;15(12):1792-1810. The Journal of Sexual Medicine can be contacted at: Elsevier Sci Ltd, The Boulevard, Langford Lane, Kidlington, Oxford OX5 1GB, Oxon, England.

Our news journalists report that additional information may be obtained by contacting B.B. Reeve, Duke University, Sch Med, Dept. of Populat Hlth Sci, Durham, NC 27705, United States. Additional authors for this research include K. Weinfurt, M. Wang, D.S. Usinger, R.C. Chen and K.E. Flynn.

The direct object identifier (DOI) for that additional information is: https://doi.org/10.1016/j.jsxm.2018.09.015. This DOI is a link to an online electronic document that is either free or for purchase, and can be your direct source for a journal article and its citation.

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