Newswire (Published: Tuesday, November 27, 2018, 11:41:00 AM CST, Received: Tuesday, November 27, 2018, 11:42:03 AM CST)
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The first prostate precision medicine trial to use liquid biopsies for genomic testing
After the liquid biopsy analysis, patients with specific DNA markers are assigned to one of five new therapies targeted at their unique form of prostate cancer. Researchers want to see if the markers identified in the screening process can help predict which patients will be helped the most by the targeted treatments.
"There is an urgent need to find more effective therapies for men with advanced prostate cancer and an individual's cancer is unique, so a one-size-fits-all solution may not be the best," says Dr.
Jim, a trial participant, shares his experience: "When I was first diagnosed with prostate cancer, I understood that this type of cancer was not good. I was offered the chance to receive a new potential treatment and I was willing to try anything that might make a difference. They sent my blood to be tested in BC and then I was enrolled, it was simple. Now I take my new treatment pills and track any side effects."
Although tumour samples taken at diagnosis can be tested for DNA markers, in order to provide current genomic information patients would need an additional invasive biopsy. Using a liquid biopsy to provide the updated information could remove the need for surgery.
"The technology and computation required to study a person's cancer using only a blood sample is very novel and experimental. This team has helped lead the charge for liquid biopsies to be part of prostate cancer clinical research," says Dr.
Canadian research innovation and collaboration - The IND.234 trial is a perfect example of Canadian excellence in research and innovation translating into new treatment approaches. The trail is supported by a core grant from the