Newswire (Published: Wednesday, November 27, 2019, Received: Wednesday, November 27, 2019, 5:21:02 PM CST)

Word Count: 463

2019 NOV 27 (NewsRx) -- By a News Reporter-Staff News Editor at Disease Prevention Daily -- Investigators discuss new findings in Oncology - Prostate Cancer. According to news reporting originating in Newark, Delaware, by NewsRx journalists, research stated, “To examine the association of smoking history and multiple measures of smoking intensity and duration with risk of biochemical recurrence in men treated for prostate cancer. We conducted a prospective cohort study of 1641 men (773 ever-smokers) treated with radical prostatectomy or radiation between 2003 and 2010.”

Funders for this research include DOD Prostate Cancer Research Program, Foundation for Barnes-Jewish Hospital, Siteman Cancer Center, St. Louis Men’s Group Against Cancer.

The news reporters obtained a quote from the research from the University of Delaware, “The association between ever-smoking and risk of biochemical recurrence was examined using Cox Proportional Hazards models with adjustment for confounders. Among ever-smokers, we further assessed the association between multiple measures of smoking duration and intensity and risk of biochemical recurrence. In the full cohort, we observed no association between ever-smoking and risk of biochemical recurrence. However, among ever-smokers, a smoking duration of greater than or equal to 10 years was significantly associated with biochemical recurrence (hazard ratio: 2.32, 95% confidence interval: 1.01, 5.33). Our results also suggested that greater than or equal to 10 pack-years of smoking may be associated with an increased risk of biochemical recurrence (hazard ratio: 1.75, 95% confidence interval: 0.97, 3.15). No association was observed between packs smoked per day or years since smoking cessation (among former smokers) and risk of biochemical recurrence.”

According to the news reporters, the research concluded: “Smoking duration is a significant predicator of biochemical recurrence among men with prostate cancer who are current or former smokers.”

For more information on this research see: Smoking History, Intensity, and Duration and Risk of Prostate Cancer Recurrence Among Men With Prostate Cancer Who Received Definitive Treatment. Annals of Epidemiology, 2019;38():4-10. Annals of Epidemiology can be contacted at: Elsevier Science Inc, Ste 800, 230 Park Ave, New York, NY 10169, USA. (Elsevier - www.elsevier.com; Annals of Epidemiology - http://www.journals.elsevier.com/annals-of-epidemiology/)

Our news correspondents report that additional information may be obtained by contacting S. Khan, University of Delaware, College of Health and Science, Epidemiology Program, 100 Discovery Blvd, 7TH Floor, Newark, DE 19713, United States. Additional authors for this research include S. Thakkar and B. Drake.

The direct object identifier (DOI) for that additional information is: https://doi.org/10.1016/j.annepidem.2019.08.011. This DOI is a link to an online electronic document that is either free or for purchase, and can be your direct source for a journal article and its citation.

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